Corona Virus spreading ... US official says no need to worry

Coronavirus crackdown? Seattle-area official outlines possible next steps

Seattle area public-health officials are “at the ready” to start ordering involuntary isolation and quarantines and are considering cancellation of major public events, with information coming soon, a top official said Monday.

Patty Hayes, director of Public Health — Seattle & King County, outlined potential next steps in the area’s effort to slow the spread of the virus at a Seattle City Council meeting and said officials are talking about what to do.

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• 6th patient dies from Cov-19 in UK
  
  US CDC Chief: "the US is beyond virus containment in some areas"
  
  Washington State considering "Rapid Lockdown", new benefits announced for workers
  
  Mortality rate in Lombardy hits 8% - higher than Wuhan
  
  Lagarde calls on European governments to embrace "rapid fiscal action."
  
  Austria, Switzerland close borders with Italy
  
  NJ Governor declares state of emergency
  
  North Carolina declares state of emergency
  
  Air Canada latest airline to suspend routes to Italy as traffic expected to plunge due to quarantine
  
  Mass. declares state of emergency after confirming 51 'presumptive' cases; Boston cancels St. Patricks Day Parade
  
  NYC Mayor says outbreak "evolving very rapidly"
  
  Harvard moves classes online
  
  Xi takes victory lap in Wuhan
  
  Trump says had 'great' meeting with Repubs on stimulus plan, but no details released
  
  Italy reports 36% jump in deaths, cases climb above 10,000
  
  Three Canadians test positive in Calgary
  
  Spain suspends parliament after lawmaker infected
  
  Austria total cases hits 182
  
  First case reported in Philly
  
  EU suspends parliament indefinitely
  
  Italian government suspends mortgage payments across country
  
  CDC says nearly 5,000 tests have been conducted in US through Monday
  
  National Guard is deploying to New Rochelle, area businesses, schools will close, Cuomo says
  
  New Jersey confirms first death
  
  Trump arrives on Capitol Hill to discuss stimulus plan with Republicans

COVID-19: Why I’m Very Concerned
— Despite what should have been ample warning, the U.S. may get blindsided

Martin Makary MD, MPH

While it’s well known that China and Iran have under-reported their COVID-19 statistics, Italy has been fully transparent. What we are learning is very concerning. The Lombardy province alone has experienced a surge in deaths due to the coronavirus— from 20 to 66 deaths in just one day. Analyzing data for the country as a whole, new diagnoses and deaths are doubling every few days. At this rate, Italy’s entire healthcare system will be overwhelmed by next week. Remember that two weeks ago, Italy had reported seven deaths.

Italy is a preview of what we may see in the U.S. very soon.

In a recent statement, the American Hospital Association projects strain on U.S. hospitals and is requesting congressional funding for new hospital construction and increased housing for patients. Doing the math, the U.S. currently has approximately 100,000 ICU beds with most hospitals already functioning at full or near-full capacity. According the Johns Hopkins Center for Health Security, 200,000 to as many as 2.9 million patients could present to U.S. hospitals with coronavirus. It’s time we increase the capacity of our medical centers before the infection ramps up.

Wuhan was overrun even with 19 field hospitals set up for the pandemic. Healthcare workers are at the highest risk of getting infected, not only representing a risk to our lives but a strain to our capacity to care for the tsunami of patients expected. U.S. hospitals and health professionals are on track to soon be overrun with patients, following the pattern of hospitals overseas who describe rationing respiratory support. Within weeks, U.S. hospitals may be significantly under-resourced and deal with major staffing shortages. Washington State is already scrambling to hire hundreds of travel nurses to help staff the influx of infected patients.

If the virus stays on its current trajectory, what happened in Wuhan will happen in the U.S. There is no strong scientific argument to suggest otherwise. While we all hope the virus demonstrates an unexpected heat-sensitivity or mutates to a less virulent form, the virus has, so far, followed a highly predictable course. That path was mapped out over 3 week ago by Marc Lipsitch, PhD, of the Harvard T.H. Chan School of Public Health. Despite his dire warning that 40%-70% of the population could be infected, little was done to prepare for the pending crisis beyond standard handwashing and coughing instructions — a routine done every flu season. We need to mobilize quickly. In a national survey of 6,500 nurses in 48 states released last week, 63% of nurses report that they do not have access to N95 respirators in their units and many said they haven't been fitted or trained on how to properly use them. At the same time, first responders are underprepared and most have not been given the protective gear they need to treat infected patients.

Unfortunately, we live in an era of people spouting opinions on social media and cable news with no knowledge of a topic. TV pundits with no knowledge of virology, public health, or pandemic history are crowding out medical experts. Twitter, which promotes shouting over listening, is also loaded with comments ignorant the to the data. News networks should push aside legacy political commentators and put infectious diseases physicians on the air to warn the public about the pandemic. Now more than ever, physicians need to speak up about the pending health crisis in the U.S.

Arguments about the exact case fatality rate (CFR) have become a distraction from the real issue at hand — preparedness. While it’s a worthy exercise to determine if CFR estimates are including mild or asymptomatic patients in the denominator, it does not change our need to prepare or how we treat individual patients. Data from Italy suggests the CFR may be as high as 3%-4%. Adding an assumption that roughly half of people with mild or no symptoms were not tested, it may be closer to 1.5%-2%, just below that of the 1918 Spanish flu pandemic which killed 30 million people. The Diamond Princess ship was a controlled case study: 705 people tested positive for the virus, and seven died, suggesting a 1% CFR, albeit a slightly older skewed population. Regardless of where the true CFR is between 1% and 3.4% as the WHO is reporting, this is, at best, at least 10 times worse than a bad flu season and at worst, a pandemic that could claim millions of American lives.

Further hindering public health efforts, the concept of American exceptionalism has morphed into a societal arrogance that somehow the immune systems of Americans are stronger than those of the Chinese. And even though other countries have enacted very strict quarantine practices, including martial law and a shutdown of schools, there is a misleading perception that the U.S. would have less community transmission because of a better health care system and better hygiene. Another barrier has been the exaggerated notion that COVID-19 is only a danger to old people and that young people are entirely resilient.

Italy has now quarantined approximately 60 million people, and closed all nightclubs, gyms, and sporting events. I respect NIAID Director Anthony Fauci and admired his leadership as a clinical voice of reason amidst of our AIDS, SARS, and Ebola epidemics, but I’m concerned he has not yet introduced contingency plans for any of these major preventive measures. Instead, he is re-iterating a popular view that there is a lot we don’t know and that anything is possible. His only strong warning has been directed at to those considering cruise ship travel. Based on the current trajectory of the pandemic, all U.S. schools are at risk and may need to be closed, public gatherings like NCAA tournament games may need to be postponed, businesses should have their employees work from home whenever possible, and hospitals should staff up. I don’t like it, but that’s what the data are telling us to do.

At the current rate of spread, we can expect members of Congress, and even presidential candidates, to be infected with the virus within 6-8 weeks. In fact, President Xi Jinping of China has not been seen in public for weeks, and many of Iran’s leaders have the infection. Already, U.S. Sen. Ted Cruz and several House members have announced they will self-quarantine after shaking hands with an infected individual. Many more are likely infected but a we have been using a false pretense that confirmed cases are the only cases out there, despite that fact that testing has been extremely limited at best. It’s time we dispel the notion that this virus is somehow contained. It is at large.

The main talking points issued on this topic have been that we simply don’t know what this virus will do -- but COVID-19's course has already played out in other parts of the world. We just need to listen to data and put medical experts out in front of this instead of broadcasting opinions. We need to plan for the worst and hope for the best. Considering the implications for public health, and particularly for our older patients and those with underlying risk factors, we should act swiftly on the data rather than risk a delayed response we might regret.​

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